WebThe EZH2, EED, and SUZ12 genes encode proteins that comprise core components of the polycomb repressive complex 2 (PRC2), an epigenetic "writer" with H3K27 … Web19 Department of Radiology, University of British Columbia, Vancouver, British Columbia, Canada. 20 Diagnostic and Medical Imaging Services, Surrey Memorial Hospital, Surrey, …
Subset of Suz12/PRC2 target genes is activated during ... - PubMed
WebFusion of JAZF to SUZ12 often occurs in endometrial stromal sarcoma, but the effects of JAZF1-SUZ12 on chromatin and cell differentiation are not understood. Tavares et al. … Web6 gen 2024 · In addition, the relative expression of SUZ12 in PNH patients was positively correlated with Ret% and the proportion of PNH clones. When we knocked down SUZ12 expression in a PIGA knockdown THP-1 cell line (THP-1 KD cells), the trimethylation of histone H3K27(H3K27me3) and cell proliferation decreased, apoptosis increased, and … grocery king clark ave
Polycomb repressive complex 2 component Suz12 is …
WebZinc fingers. Name. SUZ12 polycomb repressive complex 2 subunit. Description. This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. The specific function of this gene has not yet been determined. Web21 mar 2024 · GeneCards Summary for SUZ12 Gene. SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit) is a Protein Coding gene. Diseases associated with SUZ12 include Imagawa-Matsumoto … grocery key gulf of mexico